Effects of 8 Weeks Resistance Training on the Expression of MicroRNAs Associated With Adipose Tissue Angiogenesis in Rats on a High-Fat Diet

Background and Aim: Recent research has shown that microRNAs (miRNAs) can be regarded as new biomarkers for metabolic angiogenesis-related diseases. This study aimed to investigate the effect of 8 weeks resistance training on expression miRNAs associated with adipose tissue angiogenesis in rats a high-fat diet. Materials Methods: Forty male Wistar were randomly divided into four groups (each 10 rats): normal diet, diet+resistance training, training. The performed 5 sessions protocol each week weeks. After one familiarity ladders, 2nd week, weights 30% body weight attached rats’ tails, which gradually reached about 180% their by end To evaluate diet miR-221, miR-222, miR-329, vascular endothelial growth factor (VEGF) variables, sampling mesenteric was immediately after killing animals. Results: levels VEGF group+normal group+high-fat increased significantly compared control (P=0.001, P=0.001, respectively). However, no significant difference observed any regarding miR-329 (P=0.103). Conclusion: results showed